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Clinicians are signposted to advice on making decisions using NICE guidelines, available here

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In one report, 83% of herbal products switched the active ingredient to something else

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In an early phase 1 study of healthy obese participants, setmelanotide demonstrated significant weight loss compared to baseline for all treatment groups receiving 0.01 mg/kg/24 h via SC infusion (NCT02431442) (85, 86)

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